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KMID : 1234520100050010001
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Korean Journal of Urogenital Tract Infection Inflammation
2010 Volume.5 No. 1 p.1 ~ p.12
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Clinical Guideline of Gonorrhea
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Moon Kyung-Hyun
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Abstract
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Gonorrhea is a worldwide sexually transmitted disease (STD) caused by Neisseria gonorrhoeae. Gonorrhea is the second most often reported STD in the United States behind Chlamydia. An estimated 600,000 people each year in the United States are infected. Only about half this number of cases are reported. Infection with Neisseria gonorrhoeae, a gram-negative diplococcus, is an important cause of cervicitis, urethritis, and pelvic inflammatory disease (PID). Untreated or inappropriately treated gonorrhea can lead to significant morbidity and mortality such as PID, infertility in both males, and females, amplification of HIV transmission, eye infections, and first trimester spontaneous abortions. Given the scale of the public health impact of gonorrhea, selection of appropriate therapy for gonorrhea is essential. However, the selection of appropriate therapy for gonorrhea is complicated by theability of Neisseria gonorrhoeae to develop resistance to antimicrobial therapies. Key areas addressed include the criteria used to select effective treatment for gonorrhea, the level of antimicrobial resistance at which changing treatment regimens is recommended, the epidemiology of resistance, and the use of quinolones, cephalosporins, and other classes of antimicrobials for the treatment of uncomplicated gonorrhea. The aim of the present review were to recommend effective antimicrobial drugs for the treatment of gonorrhoea considering to the antimicrobial susceptibility and resistance of Neisseria gonorrhoeae in Korea.
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KEYWORD
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Gonorrhea, Sexually transmitted disease, Antimicrobial resistance
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